12 results
57y · Female·Multi-organ failure due to drug-induced liver injury caused by sodium valproate …
Mrs Doherty, a 57-year-old woman with CADASIL syndrome, was prescribed sodium valproate for migraine prophylaxis in November 2019. She developed acute hepatitis approximately 5 months later, presenting with jaundice, nau…
26y · Male·Multi-organ failure due to pneumococcal septic shock
A 26-year-old man presented with chest and abdominal pain, initially diagnosed with possible hepatitis based on elevated liver function tests. He developed an atypical blanched rash not recognised as varicella zoster (ch…
33y · Male·Haemoperitoneum secondary to lacerated spleen as a result of peritoneal ascitic …
A 33-year-old man with severe alcoholic liver disease (Child-Pugh C) and poor prognosis died from haemoperitoneum following splenic laceration during a diagnostic ascitic tap procedure. Two junior doctors (HMOs/Basic Phy…
64y · Male·bronchopneumonia and sepsis with chronic obstructive pulmonary disease in a man …
Edward Ivan Africh, a 64-year-old sentenced prisoner, died from bronchopneumonia and sepsis with chronic obstructive pulmonary disease (emphysema) in the setting of advanced chronic myelomonocytic leukaemia and heart fai…
59y · Male·complications of viral liver cirrhosis with hepatocellular carcinoma
Mervyn Morgan, aged 59, died from complications of hepatocellular carcinoma arising from cirrhosis while in prison custody. Critical failures included: delayed monitoring of known liver cirrhosis (no ultrasound despite M…
62y · Female·Hypovolaemic and cardiogenic shock (hysterectomy) in the context of cardiomegaly…
A 62-year-old woman with significant comorbidities (cirrhosis, cardiomegaly, thrombocytopenia, chronic kidney disease, COPD) died from hypovolaemic and cardiogenic shock during elective total laparoscopic hysterectomy fo…
62y · Male·metastatic hepatocellular carcinoma
Michael Anthony Curran, a 62-year-old prisoner, died from metastatic hepatocellular carcinoma in 2015. He had been diagnosed with hepatitis C in 2005, which is a significant risk factor for liver cancer. A liver biopsy i…
56y · Male·urosepsis
Duncan John Hancott, aged 56, died in Mount Gambier Prison from urosepsis secondary to urinary tract infection caused by E. coli. He had significant comorbidities including hepatic cirrhosis, portal hypertension, and his…
47y · Male·Complications of cirrhosis and metastatic hepatocellular carcinoma
Lance Robert Nikkelson, a 47-year-old Aboriginal man in prison custody, died from complications of cirrhosis and metastatic hepatocellular carcinoma. He presented with abdominal pain in May 2019, initially assessed as co…
41y · Male·Fulminant sepsis (Klebsiella pneumoniae) with multi-organ failure complicating s…
A 41-year-old man with newly diagnosed severe Crohn's colitis was prescribed 6-mercaptopurine (6-MP) after only 5 days of hospital treatment. He had a homozygous TPMT gene deficiency (present in ~0.3% of population) that…
37y · Male·combined ethanol and drug toxicity
Kenneth Agnew, a 37-year-old man resident in aged care, died from combined ethanol and drug toxicity involving methadone and benzodiazepines. He had hepatitis C and fatty liver disease. Critical clinical lessons include:…
17y · Female·raised intracranial pressure due to hepatic encephalopathy related cerebral oede…
Jacqueline Wood, aged 17, died from hepatic encephalopathy-related cerebral oedema following fulminant liver failure caused by paracetamol overdose. She ingested approximately 90 paracetamol tablets on 3 June 2002 but di…
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