Coronial
VIChospital

Finding into death of Baby AA

Deceased

Baby AA

Demographics

0y, female

Coroner

Coroner Jacqui Hawkins

Date of death

2018-07-21

Finding date

2020-06-29

Cause of death

Disseminated Herpes Simplex Virus (HSV 1)

AI-generated summary

An 11-day-old neonate died from disseminated HSV-1 infection acquired perinatally. She presented with sepsis-like symptoms including lethargy, poor feeding, fever and respiratory signs. Clinical management was appropriate and timely, with empirical antibiotics initiated for suspected bacterial sepsis. HSV was not suspected due to lack of documented maternal genital HSV or postnatal exposure. A delay occurred in communicating abnormal coagulation results from the laboratory, which were initially thought contaminated. While earlier lumbar puncture and cranial ultrasound would have been appropriate, the coroner found these would not have changed the outcome. The death was unavoidable given the rapid progression of disseminated disease and high mortality rate (70% untreated, 29% treated). System improvements implemented include clearer escalation pathways for critical pathology results.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.

Specialties

neonatologypaediatricspathologyobstetrics

Error types

diagnosticcommunicationdelay

Drugs involved

benzyl penicillingentamicinflucloxacillinceftriaxonephytomenadionefresh frozen plasmacryoprecipitateparacetamol

Clinical conditions

disseminated herpes simplex virus infectionneonatal herpessepsispneumoniahepatitisdisseminated intravascular coagulationmetabolic acidosisintracranial haemorrhage

Procedures

intubationnasogastric tube insertionchest X-raycranial ultrasound

Contributing factors

  • Perinatal acquisition of HSV-1 from maternal genital infection
  • Rapid progression of disseminated disease
  • Delay in recognising and communicating markedly abnormal coagulation results
  • Difficulty diagnosing HSV in disseminated disease presenting as sepsis-like illness

Coroner's recommendations

  1. Northern Hospital should consult with Victorian paediatric tertiary hospitals such as the Royal Children's Hospital and the Monash Children's Hospital regarding the process of alerting clinicians of abnormal/unexpected coagulation results in children aged under 12 years, and what should occur in the event of contaminated or unreliable results, to ensure alignment with standard Victorian practice
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