upper gastrointestinal bleed with haemodynamic compromise following anticoagulation for atrial fibrillation
AI-generated summary
Margaret Patricia Kenney, 83, died from upper gastrointestinal bleeding complicated by cardiac arrest while anticoagulated for atrial fibrillation. She had been diagnosed with gastro-oesophageal reflux disease (GORD) in 2015 and prescribed pantoprazole 40mg daily. During her final hospital admission (29 October to 13 November 2017), pantoprazole was not administered or documented as withheld, despite no clear clinical rationale. The coroner accepted expert opinion that a gastric or duodenal ulcer causing the fatal haemorrhage would likely have been prevented had PPI therapy continued, particularly in a patient receiving anticoagulation. Additional failures included lack of surgical review for undifferentiated abdominal pain, inadequate symptom investigation, and poor medication documentation. The coroner found the death was likely preventable.
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Specialties
general medicinecardiologysurgeryemergency medicine
discontinuation of proton pump inhibitor (pantoprazole) without documented rationale
lack of surgical review for undifferentiated abdominal pain
thyrotoxicosis
congestive cardiac failure
atrial fibrillation requiring anticoagulation
hypertension
diabetes mellitus type II
treatment of symptoms without investigation of underlying cause
inadequate medication documentation
Coroner's recommendations
All cases involving undifferentiated abdominal pain should be reviewed by the surgical team in the first instance regardless of abdominal imaging results
Clear and unambiguous documentation must be maintained concerning any medications being withheld, including the rationale for withholding
When medications must be withheld, alternative agents should be sought to continue treating pre-existing chronic diseases
For patients on proton pump inhibitors, there should be clear assessment of ongoing need for the drug, with alternative PPI agents prescribed if indicated, particularly for patients receiving anticoagulation
Symptoms such as nausea and vomiting should prompt investigation of underlying cause rather than symptomatic treatment alone
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