Coronial
QLDhospital

Mr B - Non-inquest findings

Deceased

Mr B

Demographics

84y, male

Coroner

Kirkegaard

Date of death

2015-03-16

Finding date

2016-02-29

Cause of death

Acute myocardial infarction precipitated by upper gastrointestinal haemorrhage from gastric ulcer in context of rivaroxaban therapy

AI-generated summary

An 84-year-old man with multiple comorbidities was prescribed rivaroxaban for deep vein thrombosis despite being a practicing Jehovah's Witness who refused blood transfusions. Rivaroxaban cannot be monitored or reversed, unlike warfarin. He developed upper gastrointestinal bleeding from a gastric ulcer, possibly exacerbated by concurrent use of a naturopathic cherry juice product and rivaroxaban. Symptoms were masked and presented as anaemia. Critical learning points: anticoagulant choice should consider patient's transfusion refusal status; clinical discharge summaries must reach GPs; a 40% haemoglobin drop warrants urgent action rather than waiting for specialist review; and symptoms of GI bleeding can be subtle in elderly patients on anticoagulants.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.

Specialties

cardiologyhaematologygastroenterologyintensive caregeneral practiceemergency medicine

Error types

medicationcommunicationdiagnosticdelay

Drugs involved

rivaroxabanenoxaparinwarfarincolchicinenature's goodness joint formula cherry juice concentrate with anthocyanin complexerythropoietinphytomenadionetranexamic acidproton pump inhibitoradrenaline

Clinical conditions

deep vein thrombosisupper gastrointestinal haemorrhagegastric ulceracute myocardial infarctionischaemic heart diseaseischaemic cardiomyopathycongestive cardiac failuretype 2 diabetes mellituschronic kidney diseaseacute kidney injurysevere anaemiacellulitisgout

Procedures

doppler ultrasoundupper gastrointestinal endoscopyendoscopic injection of adrenalineemergency resuscitation

Contributing factors

  • Prescription of rivaroxaban (non-reversible anticoagulant) to patient with faith-based refusal of blood products
  • Lack of discussion with patient about anticoagulation risks and transfusion implications
  • Concurrent use of naturopathic cherry juice product masking symptoms
  • Failure to provide clinical discharge summary to general practitioner
  • Delayed recognition of upper gastrointestinal bleeding by general practitioner
  • Missed opportunity for earlier escalation after 40% haemoglobin drop on 11 March 2015
  • Acute kidney injury making rivaroxaban less suitable than warfarin

Coroner's recommendations

  1. Ensure clinician discussion with any patient started on anticoagulation therapy about treatment risks, lack of reversal agents for new oral anticoagulants, and patient's position on accepting blood transfusions
  2. Ensure hospital pharmacy department involvement in patient education about anticoagulant risks with documentation in patient chart
  3. Require documentation in patient chart of commencement of therapy and reasons for medication decisions
  4. Improve documentation of discussions to confirm patient understanding and acceptance of treatment
  5. Better document patient requests regarding treatment and discharge preferences
  6. Improve communication within treating teams, particularly regarding medication changes and clinical reasoning
  7. Advocate for changes to national medication chart patient education box to include reference to new oral anticoagulants and reversal agent status
Full text

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