Mr B - Non-inquest findings
Deceased
Mr B
Demographics
84y, male
Date of death
2015-03-16
Finding date
2016-02-29
Cause of death
Acute myocardial infarction precipitated by upper gastrointestinal haemorrhage from gastric ulcer in context of rivaroxaban therapy
AI-generated summary
An 84-year-old man with multiple comorbidities was prescribed rivaroxaban for deep vein thrombosis despite being a practicing Jehovah's Witness who refused blood transfusions. Rivaroxaban cannot be monitored or reversed, unlike warfarin. He developed upper gastrointestinal bleeding from a gastric ulcer, possibly exacerbated by concurrent use of a naturopathic cherry juice product and rivaroxaban. Symptoms were masked and presented as anaemia. Critical learning points: anticoagulant choice should consider patient's transfusion refusal status; clinical discharge summaries must reach GPs; a 40% haemoglobin drop warrants urgent action rather than waiting for specialist review; and symptoms of GI bleeding can be subtle in elderly patients on anticoagulants.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.
Error types
Drugs involved
Clinical conditions
Contributing factors
- Prescription of rivaroxaban (non-reversible anticoagulant) to patient with faith-based refusal of blood products
- Lack of discussion with patient about anticoagulation risks and transfusion implications
- Concurrent use of naturopathic cherry juice product masking symptoms
- Failure to provide clinical discharge summary to general practitioner
- Delayed recognition of upper gastrointestinal bleeding by general practitioner
- Missed opportunity for earlier escalation after 40% haemoglobin drop on 11 March 2015
- Acute kidney injury making rivaroxaban less suitable than warfarin
Coroner's recommendations
- Ensure clinician discussion with any patient started on anticoagulation therapy about treatment risks, lack of reversal agents for new oral anticoagulants, and patient's position on accepting blood transfusions
- Ensure hospital pharmacy department involvement in patient education about anticoagulant risks with documentation in patient chart
- Require documentation in patient chart of commencement of therapy and reasons for medication decisions
- Improve documentation of discussions to confirm patient understanding and acceptance of treatment
- Better document patient requests regarding treatment and discharge preferences
- Improve communication within treating teams, particularly regarding medication changes and clinical reasoning
- Advocate for changes to national medication chart patient education box to include reference to new oral anticoagulants and reversal agent status
Full text
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