Hypoxic-ischaemic encephalopathy due to prolonged hypoxia
AI-generated summary
A 45-year-old man died from hypoxic-ischaemic encephalopathy following cardiopulmonary arrest 11 hours after elective wrist plate removal surgery. Multiple contributing factors were identified: undisclosed obstructive sleep apnoea, morbid obesity, possible respiratory infection detected intraoperatively, and post-operative medication management. Critical issues included failure to perform adequate pre-anaesthetic risk assessment, inadequate documentation and observation of sedation levels despite published PCA guidelines, non-contact with the Acute Pain Management Service when clinical deterioration occurred, and lack of escalation to senior medical staff. The patient received Temazepam and Phenergan (both CNS depressants) without consulting the pain management service as required by PCA protocol. Nursing observations were incomplete, inconsistently recorded, and the patient was transferred between wards without proper clinical handover of concerning findings, disrupting continuity of care. Lessons include: formal pre-operative risk assessment for high-risk patients, adherence to PCA safety protocols requiring pain service consultation before co-prescribing sedatives, reliable sedation scoring and observation practices, and appropriate escalation when clinical concerns arise.
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Specialties
anaesthesiapain medicineorthopaedic surgeryintensive care
open reduction and internal fixation of fractured radiusremoval of wrist plategeneral anaesthesiapatient-controlled analgesia
Contributing factors
Undisclosed obstructive sleep apnoea not revealed at pre-operative assessment
Morbid obesity (BMI 40)
Probable respiratory infection or pneumonia (brown secretions in endotracheal tube)
Morphine via patient-controlled analgesia device
Temazepam and Phenergan co-prescribed without Acute Pain Management Service consultation
Inadequate pre-anaesthetic risk assessment on day of surgery
Incomplete and unreliable nursing observations and documentation
Non-contact with Acute Pain Management Service when clinical deterioration occurred
Transfer to another ward disrupting continuity of care
Insufficient intervals between observations in ward 8AN
Opioid tolerance not reliably documented
Failure to escalate to senior medical staff
Coroner's recommendations
Review and strengthen the integrated pre-operative assessment process to ensure patients with significant risk factors (morbid obesity, sleep apnoea risk factors, uncontrolled pain requiring narcotics) are referred for formal anaesthetic risk assessment by an anaesthetist prior to the day of surgery
Ensure anaesthetists do not conduct first patient assessment on the day of elective surgery; postpone procedures if pre-operative assessment reveals uncontrolled or poorly understood medication regimes or undisclosed risk factors
Implement systems to ensure completion of integrated assessment forms with explicit identification of anaesthetic risk factors including sleep apnoea screening
Establish and enforce mandatory protocols requiring consultation with the Acute Pain Management Service before co-prescribing sedatives (such as Temazepam) with patient-controlled analgesia morphine
Provide mandatory education to all medical and nursing staff involved in post-operative care regarding PCA safety protocols and the prohibition on sedative co-prescription without pain management service consultation
Implement sedation scoring systems and comprehensive observation protocols for patients on PCA, including assessment of level of consciousness, respiratory rate, oxygen saturation, temperature, and carbon dioxide levels (not relying on oxygen saturation alone)
Establish clear guidelines that observations for PCA patients must continue at specified intervals (hourly for first 4-6 hours, then two-hourly) and be reliably recorded on the appropriate acute observation form
Ensure accurate, contemporaneous documentation of all observations on the correct charts; implement systems to prevent alteration or overwriting of clinical records
Establish protocols requiring direct contact between ward staff and the Acute Pain Management Service when a patient on PCA develops clinical concerns (drowsiness, low oxygen saturation, behavioural changes), rather than delaying or transferring to another ward
Ensure continuity of care by conducting thorough clinical handovers when patients on PCA are transferred between wards, including review of recent observations and clinical trajectory
Train ward supervisors and nursing staff to escalate clinical concerns to senior medical staff and specialist services rather than managing behavioural incidents in isolation; ensure clear pathways to on-call anaesthetists and pain management services are understood
Review policies regarding patient transfer decisions to ensure such decisions are made on clinical grounds and documented as such, rather than for social or staff convenience reasons
Establish clear escalation protocols for junior doctors (ward call doctors) to contact senior registrars or consultants when facing complex post-operative pain management situations, and to formally request senior attendance rather than offering passive consultation
Implement training for junior medical staff regarding specialist services available 24/7, particularly the Acute Pain Management Service, and the indications for their involvement
Review anaesthetic and pain management guidelines within the hospital regarding background infusion rates for PCA morphine, sedating medication interactions, and monitoring requirements, particularly in high-risk patients (obese, suspected sleep apnoea, opioid tolerant)
Facilitate ongoing liaison between the hospital and the Australian Society of Anaesthetists regarding debate over safe levels of anaesthetic and sedating medications, background infusion protocols, and monitoring practices
Consider policy review regarding intensive care admission thresholds for post-operative patients with risk factors for respiratory depression (obesity, sleep apnoea, respiratory infection) to ensure close monitoring
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