Woodcock 2011 06 14 12 49 10 862
Deceased
Liam Woodcock
Demographics
male
Date of death
2006-06-29
Finding date
2010-09-03
Cause of death
Myocardial failure resulting from excessive pulmonary blood flow and consequential loss of systemic blood flow upon a background of major congenital heart disease
AI-generated summary
One-month-old Liam Woodcock, born extremely prematurely at 27.5 weeks gestation weighing approximately 1 kilogram, died from myocardial failure secondary to excessive pulmonary blood flow in the context of severe congenital heart disease (pulmonary atresia with intact ventricular septum and right ventricular hypoplasia). He required prostaglandin infusion to maintain patency of a critical ductus arteriosus essential for systemic blood flow. The coroner identified several clinical management concerns: absence of blood pressure and blood gas monitoring during prostaglandin administration; possibly excessive prostaglandin dosing that created an imbalance favoring pulmonary over systemic circulation; a two-hour delay in intubating once clinical deterioration became obvious; and use of propofol for sedation during intubation, which may have contributed to myocardial depression. Despite these management issues, the infant's prognosis was grave from birth. Key lessons: implement close hemodynamic monitoring during prostaglandin use in ductal-dependent circulation, avoid propofol in cardiac-compromised neonates, and escalate intubation decisions promptly.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.
Specialties
Error types
Drugs involved
Clinical conditions
Contributing factors
- Pulmonary atresia with right ventricular hypoplasia
- Extreme prematurity at 27.5 weeks gestation
- Extremely low birth weight approximately 1 kilogram
- Administration of prostaglandin to maintain patent ductus arteriosus
- Possibly excessive prostaglandin dosing creating pulmonary-systemic circulation imbalance
- Possible myocardial depression from propofol administration
- Absence of blood pressure and blood gas monitoring
- Possible excessive oxygenation during intubation
Coroner's recommendations
- Reconsider protocol for propofol use in cyanotic congenital heart disease infants and finalize in urgent form; consider direction that propofol not be used in infants with compromised cardiac output and if used, only after senior intensivist or consultant review
- Amend Royal Hospital for Women's Stillbirth, Fetal, Neonatal and Infant Deaths Documentation and Transport Guideline to require downloading and retention of pulse oximeter data for deaths reported to the coroner
- Consider feasibility of introducing functional echo-cardiology training and technology in neonatal intensive care units within the Area Health Service jurisdiction given budgetary constraints
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