134 results for “drug interaction”
54y · Male·Toxic leukoencephalopathy (of uncertain aetiology)
David Main, 54, died from toxic leukoencephalopathy of uncertain aetiology following a ketamine-assisted oxycodone detoxification at Beleura Private Hospital. He had chronic pain from multiple injuries and opioid depende…
33y · Female·Combined drug toxicity, with thioridazine as the principal component, in the con…
Lou Ann Kelly, aged 33, died on 3 April 2003 at Royal Perth Hospital ICU from combined drug toxicity, primarily thioridazine, after consuming large quantities of prescription medications with alcohol…
49y · Male·Obstructive sleep apnoea, contributed to by the sedating effects of therapeutic …
…uctive sleep apnoea (OSA). He was sedated with benzodiazepines (Midazolam, Diazepam) and other psychotropic drugs despite known OSA risk. The coroner found he died from OSA exacerbated by sedating medications and coronar…
73y · Male·subdural haematoma from fall
Leonard Athol Long, a 73-year-old on warfarin for mechanical mitral valve replacement, fell twice during hospitalization for urinary tract infection. He was on SMZ-TMP antibiotics, which interact significantly with warfa…
46y · Female·Hypoxic brain injury due to combined drug toxicity
…n and was found in cardiac arrest. She suffered hypoxic brain injury and died. Toxicology revealed multiple drugs at low levels including methadone, diazepam, citalopram, and verapamil. The coroner found the death result…
17y · Female·mixed drug toxicity
Nicole Davies, 17, died from mixed drug toxicity after rapid methadone dose escalation during early maintenance therapy. She presented with clear s…
29y · Male·Penetrating wound to neck with vascular injury to the carotid sheath
…rotid sheath. Post-mortem examination revealed brain abnormalities suggesting predisposition to seizures or drug-induced psychosis. Despite immediate assistance from family, neighbours, police and paramedics who attempte…
33y · Male·Mixed drug toxicity (heroin, buprenorphine and benzodiazepines)
A 33-year-old man with polysubstance abuse disorder and mental illness died from mixed drug toxicity (heroin, buprenorphine, and benzodiazepines). He engaged in 'prescription shopping' across multipl…
41y · Male·undetermined
…mained undetermined. Post-mortem biochemistry suggested possible hyponatraemia (sodium 116mmol/L) and mixed drug side effects. On 30 October 2017, Mr Williamson presented with progressive sedation after receiving PRN ola…
59y · Male·Head and chest injuries sustained in a single motor vehicle crash
A 59-year-old man died from head and chest injuries sustained in a single motor vehicle crash after consuming alcohol at a hotel. His blood alcohol level was 0.202g/100mL, approximately four times the legal driving limit…
53y · Female·Combined effects of alcohol, amitriptyline, and methadone
…for AHPRA referral but identified a critical public safety issue—easy access to prescription medications by drug-dependent persons. Key lesson: integrated real-time prescription monitoring could have identified Ms Lovelo…
41y · Female·mixed drug and alcohol toxicity
Karen Louise Richards, 41 years old, died from mixed drug and alcohol toxicity on 11 January 2014. She had consumed heroin (evidenced by 6-MAM metabolite), alcohol, …
50y · Female·Potentially fatal multiple drug toxicity (oxycodone, mirtazapine, citalopram, cl…
…ld woman with epilepsy and chronic pain from a workplace wrist injury, died from potentially fatal multiple drug toxicity involving oxycodone, mirtazapine, citalopram, clonazepam, and pregabalin. She engaged in prescript…
47y · Female·Mixed drug toxicity (venlafaxine, duloxetine, mirtazapine, oxycodone, tapentadol…
… a 47-year-old woman with depression, anxiety, alcohol use disorder and chronic conditions, died from mixed drug toxicity involving multiple prescription medications. She was admitted to Brunswick Private Hospital in Oct…
29y · Female·Multiple blunt force injuries secondary to single motor vehicle crash (driver) w…
…pproximately 80 metres. Clinical lesson: alcohol impairs judgment and coordination, and combined with other drugs (ketamine) and speeding significantly increases crash risk. This preventable death highlights the dangers …
29y · Male·acute bronchopneumonia complicated by multi-drug toxicity
Nicholas Ang, aged 29, with schizoaffective disorder, died from acute bronchopneumonia complicated by multi-drug toxicity while in a psychiatric unit. Admitted 12 August 2005, he was on clozapine, valproic acid, and clon…
20y · Female·Methylamphetamine toxicity
Laura Kate Muckersie, a 20-year-old female with a history of drug use, died on 30 July 2001 from methylamphetamine toxicity. Her body was found in a storm water drain in Swa…
48y · Female·Mixed drug toxicity (morphine, codeine, venlafaxine, amitriptyline and zopiclone…
A 48-year-old woman with depression, anxiety, and bipolar disorder died from mixed drug toxicity while on voluntary inpatient psychiatric admission. She had undisclosed significant illicit drug u…
57y · Male·Aspiration pneumonia in an HIV positive man on methadone
A 57-year-old man with HIV, chronic alcoholism, and opioid dependence died from aspiration pneumonia while residing in a managed care facility. On the day of death, staff noted abnormal behaviour and drowsiness; methadon…
38y · Female·mixed drug toxicity (lethal level of dothiepin, potentially lethal level of morp…
A 38-year-old woman with long-standing heroin and benzodiazepine dependence died from mixed drug toxicity following injection of heroin. Her GP had prescribed multiple benzodiazepines (diazepam, oxazepam,…
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