Adelaide Wilson, 86 years old, presented to an urgent care centre with two days of chest pain and vomiting. A point-of-care troponin test (i-STAT) returned 0.4 ng/L, interpreted as normal, and she was discharged with gastritis. She deteriorated the next day with cardiogenic shock and died at Austin Hospital. The Austin's troponin was 329 ng/L, confirming type-II myocardial infarction. The i-STAT result was actually elevated but misinterpreted because the device printout lacked reference ranges. Critical failures included: abnormal vital signs not escalated to medical staff, no documented differential diagnosis or risk stratification, no clear responsibility for result validation, and delayed result review (12 days later). While earlier recognition may not have prevented death given her age and comorbidities, system improvements were recommended: providing reference ranges on point-of-care devices, flagging abnormal vital signs electronically, staff education on chest pain assessment, and dual checking of results.
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Specialties
cardiologyemergency medicinepathology
Error types
diagnosticcommunicationsystem
Clinical conditions
type II myocardial infarctioncardiogenic shockacute coronary syndromecomplete heart blockacute heart failurecoronary artery diseasehypertensionhypercholesterolaemia
Contributing factors
Coronary artery disease
Hypertension
High cholesterol
Misinterpreted troponin result at urgent care centre
Failure to escalate abnormal vital signs
Lack of documented differential diagnosis
Absence of risk stratification
Delayed result validation (12 days)
Point-of-care testing device without reference ranges on printout
Coroner's recommendations
Abbott point of care diagnostics should consider a software update for i-STAT-1 machines that includes reference ranges, interpretation of result and other cognitive aids
CAH and Australian Clinical Labs should reconsider a point-of-care testing machine whose print-out/interface contains reference ranges and other cognitive aids
Safer Care Victoria should consider distributing the learnings of case to health services that utilize i-STAT-1 machines
The National Association of Testing Authorities and the National Pathology Accreditation Advisory Council should consider whether current guidelines for point-of-care testing should be changed so that biological reference intervals or clinical decision values be included on point-of-care testing printouts as well as final reports
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