Cardiac failure due to atherosclerotic and hypertensive heart disease
AI-generated summary
A 66-year-old woman died from cardiac failure due to atherosclerotic and hypertensive heart disease. She presented to a rural GP with ankle oedema, cough, and palpitations during interstate travel. The GP diagnosed mild heart failure with atrial fibrillation and prescribed both a diuretic (frusemide) and a beta-blocker (sotalol) simultaneously. Sotalol should not be initiated in untreated heart failure as it can exacerbate the condition. The patient deteriorated the next day with cardiogenic shock and died despite resuscitation. Expert evidence indicated the patient likely would not have died without sotalol prescription. Key clinical lessons: cardiac failure must be excluded in older patients presenting with ankle oedema and relevant risk factors; abnormal liver function tests warrant diagnostic reconsideration; beta-blockers should only be introduced after diuresis and stabilization of heart failure; and rural GPs managing transient patients require clear guidance on high-risk medication prescribing.
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Specialties
general practicecardiologyintensive careemergency medicine
Failure to recognize severe cardiac failure on initial presentation
Prescription of sotalol (beta-blocker) in untreated/uncontrolled heart failure
Inadequate interpretation of abnormal liver function tests as indicator of cardiac failure
Simultaneous initiation of diuretic and beta-blocker without adequate diuresis first
Insufficient consideration of cardiac cause of ankle oedema in high-risk patient
Lack of appropriate escalation or hospital referral despite clinical deterioration
Coroner's recommendations
The Cardiac Society of Australia and New Zealand, in conjunction with the Royal Australian College of General Practitioners, should consider whether it is necessary to alert the general practice community to the risks involved in the prescription of Sotalol in untreated heart failure
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