William Bligh, a 9-year-old boy from Palm Island, died from disseminated melioidosis on 24 February 2013. He presented with fever and cough from 2 February, initially assessed as viral illness. Over 11 days, he was reviewed multiple times at Palm Island Hospital and diagnosed with community-acquired pneumonia on 14 February, treated with oral antibiotics. When he failed to improve, he was admitted on 20 February and given intravenous antibiotics. After further deterioration, he was transferred to Townsville Hospital on 23 February. Despite appropriate intensive care, he died within 12 hours. The coroner found his clinical care was appropriate and followed Queensland Health guidelines. Melioidosis is rare in children without identifiable risk factors, difficult to diagnose, and carries 80-95% mortality in septic shock despite appropriate antibiotics. Expert reviews concluded earlier diagnosis or intervention would not have changed the outcome. Systems issues were identified regarding escalation protocols and antibiotic timing at Townsville Hospital, but these did not affect William's prognosis.
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Specialties
paediatricsinfectious diseasesintensive caregeneral practice
melioidosisdisseminated infectioncommunity-acquired pneumoniaseptic shocksepticaemiapneumonia with septic embolisationabscessesstaphylococcal pneumonia
Procedures
intubationmechanical ventilationchest X-rayCT scan of chest and abdomenblood cultureblood test
Contributing factors
Rarity of melioidosis in paediatric patients without identified risk factors
Difficulty in diagnosis of melioidosis
Lack of specific risk factors to alert clinicians to melioidosis
Negative blood cultures at Palm Island Hospital
High bacterial load potentially from environmental exposure during wet season
Possible unrecognised predisposing immune condition
Delay in antibiotic administration at Townsville Hospital (prescribed 3.40pm, administered 8pm)
Confirmation bias in clinical assessment regarding severity
Coroner's recommendations
Confirmation bias be researched further
Training in regard to infectious diseases be revised
Guidelines be developed for communication and consultation regarding paediatric admissions to JPHS
RAT procedures be revised to provide guidelines on senior supervision, handover and maintenance of responsibilities when serious illness or instability is identified
Procedures be put in place to ensure the early administration of antibiotics in acutely unwell patients
The Therapeutic Guidelines be revised to more clearly reflect regional issues in relation to infectious diseases
The state wide CEWT committee be advised of the issues identified when the CEWT was used in this case
Formal introduction and specific training in tropical medicine be provided to JPHS medical staff
Formal guidelines be developed for referral and transfer to the Townsville Hospital
Patient Access and Flow Health Service Directive be reviewed to address risks to seriously unwell inter-hospital transfer patients
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