medication related cardiac arrest (verapamil and propranolol) in a patient with community acquired pneumonia and immunosuppression associated with treatment for rheumatoid arthritis
AI-generated summary
Mrs Patricia Croxon, a 79-year-old admitted with community-acquired pneumonia, died from medication-related cardiac arrest caused by verapamil and propranolol. The verapamil was charted in immediate release form when she had been taking slow release (Cordilox) in the community. A failure to tick a box on the medication chart indicating slow release form, combined with weekend pharmacy closures and the absence of out-of-hours pharmacist oversight, meant the error was not identified before administration. She received six tablets of immediate release verapamil at 8am on 4 August instead of slow release, causing dangerously high serum levels that peaked rapidly and depressed cardiac function alongside propranolol. The coroner made no criticism of individual clinicians but identified systemic issues. Since her death, Canberra Health Services has implemented a digital health record system requiring explicit selection of drug formulation, removed immediate release verapamil from the night cupboard, and expanded ward-based pharmacy services, changes likely to prevent such errors.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.
community-acquired pneumoniahypotensioncardiac arrhythmiahypertensiontachycardiarheumatoid arthritis with immunosuppressioncardiac arrest
Contributing factors
failure to indicate slow release formulation on medication chart
administration of immediate release verapamil instead of slow release form
absence of pharmacist oversight out of hours
weekend pharmacy reduced staffing
delayed administration of propranolol causing concurrent high serum levels
night cupboard dispensing process without real-time pharmacy review
concomitant use of verapamil and propranolol not clinically indicated
patient vulnerability from pneumonia and comorbidities
Coroner's recommendations
No specific recommendations made. The coroner declined to recommend 24-hour, 7-days-a-week pharmacy operations as this is not standard practice across Australia and involves funding decisions beyond the coroner's scope.
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