84 results for “respiratory depression”
Unknown·Toxicity to protonitazene
…onments leaves no one capable of recognising overdose or administering naloxone; and the rapid onset of respiratory depression from extreme potency provides no intervention window. Clinical lessons include recognising n…
Male·acute ethanol intoxication or positional asphyxia due to acute alcohol intoxicat…
…ng episodes. All had very high blood alcohol concentrations. The coroner emphasised that alcohol causes respiratory, cerebral and cardiac depression at these levels, and can be fatal especially with aspiration of vomitu…
70y · Male·The combined effects of the complications of ventilation associated pneumonia, a…
…he died on 17 May 2019. The cause of death was complications of ventilation-associated pneumonia, acute respiratory distress syndrome, and hypoxic ischaemic encephalopathy following an unknown triggering event. Possible…
20y · Female·Mixed drug toxicity including tramadol and flualprazolam
…ed flualprazolam. The combination of these drugs caused synergistic central nervous system sedation and respiratory depression. The coroner emphasised the dangers of illicit drugs from unregulated markets where actual c…
39y · Female·mixed prescription drug and alcohol toxicity (ethanol, tapentadol, tramadol, pro…
…had chronic complex medical conditions (breast cancer post-treatment, rheumatoid arthritis, sarcoidosis, depression, anxiety) with previous overdose attempts and suicidal ideation. She disclosed feeling like a burden but…
50y · Female·Combined drug toxicity in a woman with tension pneumothorax
… combined drug toxicity in the setting of tension pneumothorax. She had a history of alcohol dependence, depression, and borderline personality disorder. Following an argument with her partner on 7 January 2020, she was …
19y · Female·Mixed drug toxicity, with morphine (from poppy seeds) and dextromethorphan (from…
…l lessons include the danger of combining depressant substances, the critical importance of recognizing respiratory depression signs, and the need for public education about poppy seed toxicity.
16y · Male·Complications of acute alcohol intoxication
…le unconscious on an outdoor couch. Clinical lessons: acute alcohol intoxication in young people causes respiratory depression and airway compromise risk; loud snoring during unconsciousness indicates severe CNS depress…
87y · Female·heart failure and probable pneumonia in an elderly lady complicated by morphine …
… medical history, or full clinical picture. The deceased was opioid-naïve, frail, and at high risk from respiratory depression. The morphine caused toxicity with respiratory depression and was potentially lethal. Howeve…
5y · Female·Hypoxic-ischaemic Encephalopathy due to methadone toxicity
… check on LA for extended periods despite hot weather and her recent minor illness; once opioid-induced respiratory depression and hypoxia developed, naloxone proved ineffective as significant brain damage had already o…
51y · Female·Unintentional prescription drug poisoning due to central nervous system depressi…
A 51-year-old woman with chronic pain, depression, and longstanding medication misuse died from unintentional prescription drug poisoning. She had been pr…
61y · Male·mixed prescription drug toxicity (methadone, diazepam, promethazine) with aspira…
…ibed sedating medications without food. The coroner found therapeutic drug levels but noted synergistic respiratory depression from the drug combination, combined with CNS depression from alcohol, led to airway compromi…
32y · Female·Opiate toxicity; toxic combination of morphine and codeine causing respiratory d…
Mrs Edwards, a 32-year-old woman with severe depression and psychiatric history, was found dead in bed. Autopsy revealed opiate toxicity with high levels of mor…
18y · Female·Acute Alcohol Toxicity with Early Pneumonia and Aspiration
…l admission and professional airway management. Those present lacked understanding of alcohol toxicity, respiratory depression, and aspiration risk.
48y · Male·Mixed prescription drug and ethanol toxicity (promethazine, citalopram and ethan…
A 48-year-old male died from mixed prescription drug and ethanol toxicity after consuming an entire packet of promethazine tablets (approximately 80mg) while significantly intoxicated following a day of heavy alcohol con…
30y · Male·acute alcohol (ethanol) toxicity
A 30-year-old male with severe alcohol dependence died from acute ethanol toxicity after a prolonged drinking episode. Despite engagement with alcohol and drug services, counselling, and family support, he was unable to …
79y · Male·hypoxic brain injury due to cardio-respiratory arrest caused by opioid toxicity
…documentation or monitoring. Wang showed clinical somnolence from 5pm that day—an early warning sign of respiratory depression. The expert consensus was these morphine doses were inappropriate given Wang's age (79), opi…
44y · Male·Hypoxic brain injury secondary to heroin and alcohol toxicity
…om hypoxic brain injury caused by heroin and alcohol toxicity following an overdose. He had a history of depression, financial difficulties, and prior heroin use. After collapsing at a friend's home, he was resuscitated …
44y · Male·Unascertained
…ine, pregabalin) and unprescribed drugs (clonazepam, tramadol) capable of causing central nervous system depression and respiratory depression. Despite extensive investigation, the specific cause of death remained unasce…
25y · Male·Combined flualprazolam and alcohol toxicity
… as counterfeit alprazolam. The combination of benzodiazepines with alcohol produces dangerous additive respiratory depression. The coroner recommends Victorian health authorities consider harm reduction strategies incl…
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