1 result for “pupil constriction”
Coroner's Finding: SMITH Ian Myles
2y · Male·morphine toxicity
A 2-year-old boy died from morphine toxicity approximately 35 hours after suspected ingestion of up to 7 Kapanol (slow-release morphine) capsules accessed from his father's medication left unguarded in the home. Hospital care was appropriate, with nurses performing regular observations and showing good clinical vigilance. However, there was a critical transition point: detailed neurological observations (which had been half-hourly) ceased abruptly when the day shift commenced, before medical review occurred. Early signs of morphine toxicity (pupil constriction, respiratory depression) were identified overnight and managed conservatively pending possible deterioration. The child appeared clinically well on the morning of day 2, leading to discharge of siblings and continued routine management. Death occurred unexpectedly that night. The coroner found no criticism of clinical care, but highlighted that standard pharmacokinetic assumptions about morphine peak effects (3-12 hours) did not apply in this case, warranting caution in very young children with opioid ingestion.
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