Coronial
VICcommunity

Finding into death of Anthony Laurence Parisi

Deceased

Anthony Laurence Parisi

Demographics

39y, male

Coroner

Coroner Simon McGregor

Date of death

2025-03-09

Finding date

2026-03-04

Cause of death

Multidrug toxicity (GHB, methylamphetamine, ketamine) in a setting of restraint and moderate coronary artery atherosclerosis

AI-generated summary

Anthony Parisi, 39, died from multidrug toxicity (GHB, methamphetamine, ketamine) in a setting of police restraint and moderate coronary artery atherosclerosis. He consumed large quantities of GHB and methamphetamine on 8 March 2025, presented with acute behavioural disturbance requiring police care and control under mental health legislation. Paramedics appropriately administered ketamine sedation following clinical guidelines, but shortly after, Anthony developed respiratory arrest and cardiac dysrhythmias requiring prolonged resuscitation. The coroner found police restraint was lawful, proportionate and reasonable; paramedics followed appropriate clinical protocols; and no actionable prevention opportunities were identified as Anthony repeatedly declined drug treatment despite multiple hospitalisations.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.

Specialties

emergency medicineintensive careparamedicinetoxicologyforensic medicine

Drugs involved

gamma-hydroxybutyratemethamphetamineketamine

Clinical conditions

acute behavioural disturbancedrug-induced excited deliriummultidrug overdosehyperthermiahyperkalaemiahypoglycaemiacardiac dysrhythmiacirculatory collapserespiratory arrestcoronary artery atherosclerosis

Procedures

intramuscular ketamine administrationcardiopulmonary resuscitationbag valve mask ventilationendotracheal intubationintravenous cannulationextracorporeal membrane oxygenation (ECMO)

Contributing factors

  • acute toxicity from gamma-hydroxybutyrate (GHB) at supralethal dose
  • acute toxicity from methylamphetamine at potentially fatal concentration
  • ketamine administration superimposed on other drug effects
  • prolonged physical restraint with mechanical asphyxia component
  • moderate coronary artery atherosclerosis (60% stenosis)
  • hyperthermia (40.3°C core temperature)
  • hyperkalaemia
  • profound hypoglycaemia
  • excited delirium syndrome

Coroner's recommendations

  1. Finding to be provided to Secretary of Department of Health to inform development and implementation of harm reduction initiatives
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