Infective exacerbation of chronic obstructive airways disease in the setting of a medication administration error (pregabalin)
AI-generated summary
Caroline McCormack, 74, died from infective exacerbation of chronic obstructive airways disease following a medication administration error where pregabalin was erroneously included in her Webster-pak despite being ceased by palliative care. She experienced a fall due to drowsiness from the medication on 17 March, was admitted to hospital on 19 March with declining consciousness, and died 22 March. The coroner found the error resulted from systemic pharmacy failures: multiple prescribers using different communication methods (phone, fax, personal visit) and failure to update electronic records when manual changes were made. The error occurred in an error-prone environment with complex medication management. While pregabalin may have increased aspiration risk, causation to death could not be definitively established. The coroner recommended hospital discharge medication lists be sent directly to community pharmacies.
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Specialties
general practicepalliative careemergency medicinepharmacygeneral medicine
Error types
medicationsystemcommunication
Drugs involved
pregabalinmorphinemidazolam
Clinical conditions
chronic obstructive airways diseasebronchopneumoniainfective exacerbation of chronic obstructive airways diseasesystemic lupus erythematosuschronic lower back painsubclinical hyperthyroidismgastro-oesophageal reflux disease
Contributing factors
Medication administration error: pregabalin erroneously included in Webster-pak after being ceased
Multiple forms of communication (phone, fax, personal visit) between clinicians and pharmacy
Failure to update electronic packing system when manual changes were made
Outdated paper-based packing record used by dispensing pharmacist
Complex medication management with regular changes
Chronic obstructive airways disease as underlying risk factor for infection
Drowsiness from pregabalin potentially increasing aspiration risk
Coroner's recommendations
The Pharmacy Guild of Australia should consider a means by which hospital discharge medication lists could be provided directly to a patient's regular or community pharmacy, particularly where that patient relies on a Webster-pak or similar dose administration aid
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