Deceased
Stuart John Noble
Demographics
47y, male
Coroner
Coroner Audrey Jamieson
Date of death
2021-12-08
Finding date
2023-05-29
Cause of death
Multidrug toxicity (ethanol, quetiapine, baclofen, benzodiazepines)
AI-generated summary
Stuart Noble, 47, died from multidrug toxicity involving baclofen, quetiapine, benzodiazepines, and ethanol in an intentional overdose. He was prescribed baclofen off-label by his GP for alcohol use disorder despite it lacking TGA approval for this indication. The coroner identified concerning patterns: baclofen is widely prescribed off-label for alcohol use disorder, yet carries TGA warnings about suicide risk in patients with alcohol use disorder. Stuart had multiple risk factors including long-term alcoholism, mental ill-health, prior suicide attempt, and recent relationship breakdown with family violence. The coroner highlighted that despite clinical evidence supporting baclofen's efficacy, safer prescribing practices are needed for vulnerable patients, particularly those with mental health comorbidity. No formal AHPRA referral was made, but the coroner asked the RACGP to review guidance for GPs prescribing baclofen safely.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.
Specialties
Error types
Drugs involved
Clinical conditions
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