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Finding into death of Leeanne Matheson

Deceased

Leeanne Matheson

Demographics

52y, female

Date of death

2019-04-19

Finding date

2022-01-31

Cause of death

Mixed drug toxicity (methadone, pregabalin, valproic acid, benzodiazepines)

AI-generated summary

A 52-year-old woman with chronic pain, epilepsy, and opioid dependence died from mixed drug toxicity after prescribed methadone, pregabalin, valproic acid, and benzodiazepines. She was admitted to Box Hill Hospital on 12 April 2019 with suspected methadone and clonazepam overdose. An addiction medicine specialist reduced her methadone from 40mg to 20mg daily and her clonazepam from 2mg to 1mg daily. She self-discharged on 17 April 2019 with discharge summary recommending these reduced doses. However, her GP prescribed 40mg methadone on 18 April 2019—double the recommended dose—apparently unaware of the recent overdose admission and medication changes. She died two days later. The coroner identified critical communication failure: the GP did not receive or review hospital notifications of the overdose and dose reductions before re-prescribing the higher dose. Direct verbal communication between hospital and GP regarding opioid dose changes could have prevented this death.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.

Contributing factors

  • Prescription of methadone 40mg daily by GP despite recent overdose admission and specialist recommendation to reduce to 20mg daily
  • Failure of GP to receive or review hospital discharge summary documenting methadone dose reduction
  • Lack of direct communication between hospital and GP regarding changes to opioid prescriptions
  • Patient's unreliability as medical historian—did not disclose recent hospital admission to GP
  • Unclear timing of electronic discharge summary import into GP's medical record system
  • Self-discharge from hospital on 17 April 2019, interrupting planned observation period
  • Complex polypharmacy with multiple CNS depressants (methadone, benzodiazepines, pregabalin, valproic acid)
  • Patient's history of substance misuse and addiction

Coroner's recommendations

  1. Eastern Health should implement a policy requiring direct verbal communication between the hospital treating team and the patient's authorised prescriber in instances where a patient's opioid prescriptions have been changed during their inpatient stay.
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