Complications of metastatic lobular carcinoma of the breast in a woman with dementia
AI-generated summary
A 94-year-old woman with advanced dementia and metastatic breast cancer died from complications of her malignancy. She presented repeatedly with vomiting due to duodenal obstruction from metastatic tumour, but this was not diagnosed until 15 November 2017, two weeks into her final admission. A critical error occurred on 6 November when GMU clinicians mistakenly told the family that a CT scan had already been performed, when in fact no such scan had been done. This communication error delayed appropriate imaging. However, the coroner found that earlier diagnosis would not have changed management—seven separate clinical teams, including senior gastroenterologists and medical oncologists, all independently recommended palliative care only. Surgery, chemotherapy, and stenting were deemed inappropriate due to the patient's extreme frailty, advanced dementia (ECOG score 4), and terminal cancer status. The key clinical lesson is the importance of accurate communication about diagnostic investigations and documentation, though in this case, the error did not alter the inevitable outcome.
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Specialties
general medicinegastroenterologypalliative careoncologygeneral surgeryradiology
Error types
communicationdiagnosticdelay
Drugs involved
tamoxifendonepezilfosfomycinfulvestrant
Clinical conditions
metastatic lobular carcinoma of the breastduodenal obstructiondementiagastric outlet obstructionaspiration pneumoniahypernatremiagastroparesisaortic valve diseasecardiomegaly
Metastatic breast cancer with duodenal obstruction
Delayed diagnosis of metastatic disease
Mistaken belief that CT scan had been performed, delaying appropriate imaging
Communication error regarding diagnostic investigations
Advanced frailty and multiple comorbidities
Aspiration risk due to immobility and dementia
Coroner's recommendations
The Australian Commission on Safety and Quality in Health Care and SaferCare Victoria should consider the need for a body external to health organisations to conduct periodic audits within the three-year assessment windows for ongoing compliance with the National Safety and Quality Health Service Standards, particularly regarding Clinical Governance and open disclosure processes.
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