Coronial
VIChospital

Finding into death of Ms C

Deceased

Ms C

Demographics

49y, female

Date of death

2017-10-21

Finding date

2019-10-29

Cause of death

hypoxic ischaemic encephalopathy complicating cardiac arrest due to pulmonary thromboembolism in the setting of morbid obesity

AI-generated summary

A 49-year-old woman with morbid obesity, obstructive sleep apnoea, and psychiatric history was admitted following deliberate medication overdose. She was intubated, managed in ICU, then transferred to the ward where she received standard-dose heparin thromboprophylaxis (5000 units twice daily). She was discharged after 4 days but suffered a pulmonary embolism en route home, resulting in cardiac arrest and death from hypoxic ischaemic encephalopathy. The coroner found medical management reasonable and appropriate by current guidelines. However, the investigation highlighted that morbidly obese patients have increased VTE risk and may require higher prophylactic heparin doses, as standard dosing may provide suboptimal protection. No firm dosing guidelines currently exist for obese patients. The coroner recommended further evaluation of increased heparin dosages in the obese population.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.

Contributing factors

  • morbid obesity
  • obstructive sleep apnoea
  • standard-dose heparin prophylaxis potentially suboptimal for obese patients
  • increased risk of venous thromboembolism in obese population
  • lack of firm dosing guidelines for prophylactic anticoagulation in obese patients

Coroner's recommendations

  1. The Australian Commission on Safety and Quality in Health Care should further evaluate if increased dosages of thromboprophylaxis should be considered in the obese population, and if so, that a specific dosage for obese patients be included in the Therapeutic Guidelines.
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