hypoxic ischaemic encephalopathy complicating cardiorespiratory arrest in the setting of acute asthma attack
AI-generated summary
Mrs Le Hue Huynh, 46, died from hypoxic ischaemic encephalopathy complicating cardiorespiratory arrest during the November 21, 2016 Thunderstorm Asthma event in Melbourne. She had known asthma with poor medication compliance, was highly sensitized to rye grass pollen, and had hay fever. She called 000 at 6:42pm during unprecedented demand (2,332 calls in 12 hours, 397 in 30 minutes), and her family transported her to hospital where she was found in cardiac arrest. Prolonged resuscitation caused hypoxic brain injury. Clinical lessons: patients with asthma and hay fever, particularly those uncontrolled on reliever-only therapy, faced highest risk. Better preventer medication compliance, asthma action plans, allergy testing, and remaining indoors during TA warnings could have been protective. The emergency response system was overwhelmed despite appropriate surge management and inter-agency coordination.
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Specialties
emergency medicineintensive carerespiratory medicineallergy and immunologyparamedicine
thunderstorm asthma event with unprecedented surge in ambulance demand
poorly controlled asthma with sub-optimal preventer medication use
reliance on reliever medication (salbutamol) without regular inhaled corticosteroid
high sensitization to rye grass pollen
hay fever
absence of asthma action plan or management plan
no lung function testing despite history of exacerbations
exposure to outdoor environment during thunderstorm asthma event
delayed ambulance response due to system-wide surge
rapid onset severe asthma attack (approximately 15 minutes from complaint to respiratory arrest)
difficult intubation with prolonged resuscitation time
Coroner's recommendations
Further research into the specific meteorological, biological and aerobiological factors that combine to create thunderstorm asthma events to improve predictability and forecasting accuracy
Continued development and verification of the thunderstorm asthma forecasting system
Continued public awareness campaigns by DHHS regarding thunderstorm asthma, asthma action plans, and the link between hay fever and thunderstorm asthma
Further medical, allied health and community education encouraging hay fever sufferers to undergo allergy testing to understand their susceptibility to thunderstorm asthma and inform clinical management
When a thunderstorm asthma warning is issued, those at risk should remain indoors with windows and doors shut, turn off evaporative cooling or systems that draw in outside air, and/or travel to/from work later
Address the current limitation that callers during high-demand periods cannot receive estimated time of arrival information for ambulances to enable informed decisions about alternative transport to hospital
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