Shane Kyle Tatti, a 27-year-old gardener, died from complications of tiger snake envenomation. After a vigorous bite on 6 November 2014, he received one vial of tiger snake antivenom at Orbost Hospital 62 minutes post-bite, consistent with then-current guidelines. Despite appropriate initial management and rapid transfers to Bairnsdale and Austin Hospitals, he developed severe progressive myotoxicity, rhabdomyolysis, coagulopathy, renal failure and shock, dying 2 days later. The coroner found conflicting expert opinion: two toxicologists questioned whether single-dose antivenom was adequate for severe envenomings, while the guideline author argued the massive venom load caused irreversible muscle damage before antivenom could act. The case highlights uncertainty around optimal antivenom dosing in extreme envenoming cases and the tension between evidence-based population guidelines and individual clinical outliers.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.
potentially inadequate antivenom dosing (single vial vs. multiple vials)
rapid toxin movement to muscle causing irreversible myotoxicity prior to antivenom administration
severe myotoxicity leading to rhabdomyolysis with peak CK >500,000
severe coagulopathy (INR >10, APPT >120)
acute renal failure with hyperkalaemia
refractory shock
Coroner's recommendations
DHHS should again review the 2017 'Management of snake bite in emergency departments in Victoria clinical guidelines' in light of this Finding
The Australasian College for Emergency Medicine (ACEM) should circulate this Finding to ACEM fellows to highlight the evidence, guidelines and potential issues in the management of snake bite
Support for multi-centre, independent research to substantiate the appropriateness of single ampoule antivenom dosing
Clinical details of this case and other tiger snake envenomation deaths should be published in medical literature (subject to family consent) to inform clinicians
Guidelines should acknowledge potential circumstances where more than one ampoule of antivenom may be required, particularly in severe envenoming cases
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