Coronial
VIChome

Finding into death of NJ

Deceased

NJ

Demographics

35y, female

Date of death

2015-05-01

Finding date

2017-07-04

Cause of death

combined drug toxicity

AI-generated summary

A 35-year-old woman with long-standing substance use disorder, depression, and chronic pain died from combined drug toxicity involving methadone, pregabalin, methamphetamine, benzodiazepines, mirtazapine, promethazine and paracetamol. Critical clinical failures included: prescription shopping across multiple clinics (at least 4 doctors prescribing overlapping pregabalin, benzodiazepines, and mirtazapine); contraindicated benzodiazepine prescribing despite documented substance use disorder and opioid replacement therapy; long-term benzodiazepine use without cessation strategy; and unsupervised methadone dosing (5 doses weekly) despite multiple risk factors. Doctors failed to notify Drugs and Poisons Regulation despite awareness of drug dependence. No real-time prescription monitoring existed. Better coordination between prescribers, adherence to prescribing guidelines for benzodiazepines and pregabalin, supervised methadone dosing, and a prescription monitoring system could have prevented this death.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.

Contributing factors

  • prescription shopping across multiple clinics
  • excessive prescribing of pregabalin without awareness of other prescriptions
  • long-term benzodiazepine prescribing without cessation strategy
  • contraindicated benzodiazepine prescribing to opioid-dependent patient
  • failure to notify Drugs and Poisons Regulation despite evidence of drug dependence
  • unsupervised methadone dosing to unstable patient with contraindications
  • lack of inter-clinic communication and coordination
  • absence of real-time prescription monitoring system
  • inadequate assessment of pregabalin abuse potential
  • use of illicit methamphetamine in combination with prescribed drugs

Coroner's recommendations

  1. The Royal Australian College of General Practitioners should provide education to its members as to the need for caution in prescribing pregabalin due to its risk of misuse and its potential for harm
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