A 56-year-old woman presented to Knox Private Hospital with severe headache and eye symptoms on 16 June 2007. An ED physician diagnosed ischaemic stroke based on a subtle CT finding in the absence of focal neurological signs, which was not a reasonable diagnosis. She was admitted and started on anticoagulation (Clexane then heparin). When she deteriorated neurologically at 10:30pm with new visual field loss, heparin was escalated rather than stopped and urgent rescanning arranged. She had a large intracranial haemorrhage, likely secondary to anticoagulation, and died the next morning. Clinical lessons: CT findings must correlate with clinical presentation; headache without focal signs is atypical for stroke; when patients deteriorate on anticoagulation, therapy should be ceased and imaging repeated immediately, not escalated; and patients with significant neurological events should be transferred to hospitals with neurology and stroke services.
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Specialties
emergency medicineneurologyneurosurgeryintensive careradiologygeneral medicine
Misdiagnosis of ischaemic stroke based on non-diagnostic CT imaging in absence of focal neurological signs
Initiation of anticoagulation therapy (Clexane then heparin) for presumed ischaemic stroke without adequate clinical or radiological evidence
Failure to cease anticoagulation and arrange urgent rescanning when patient deteriorated neurologically at 10:30pm with new visual field defect
Escalation of heparin dose following new neurological deficit rather than investigation and cessation of therapy
Delay in transfer to specialist neurosurgical facility; emergency neurosurgery could not be performed at Knox Private Hospital due to unavailable neurosurgical nursing staff
Inadequate clinical correlation between CT findings and patient's clinical presentation; excessive reliance on imaging
Coroner's recommendations
Clinicians should ensure CT findings are correlated with patient's clinical signs and symptoms and should not be relied upon in isolation for neurological diagnosis
Hospitals should ensure protocols are established for rapid assessment and imaging of patients presenting with acute neurological symptoms
Hospitals should ensure appropriate staff are available 24/7 for emergency neurosurgical procedures
When patients deteriorate whilst on anticoagulation therapy, clinicians should immediately cease the therapy and arrange urgent rescanning rather than escalating the dose
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