right lower lobe pneumonia (Staphylococcus aureus)
AI-generated summary
A 74-year-old woman admitted for depression and functional decline following aortic valve replacement received 15mg Nitrazepam instead of prescribed 15mg Mirtazapine due to drug name confusion. The sedation caused aspiration of gastric contents, leading to hospital-acquired pneumonia (Staphylococcus aureus) and death. Contributing factors were medication name similarity, lack of drug familiarity, time pressure before transfer to another facility, and relative inexperience of junior nurse. Coroner commended hospital's remedial actions including medication administration assessments and Look-Alike Sound-Alike drug alerts. Electronic prescribing systems were identified as having potential to prevent similar errors in future.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.
Specialties
general medicinepsychiatryintensive careemergency medicine
Error types
medicationcommunication
Drugs involved
nitrazepammirtazapineflumazenilsertraline
Clinical conditions
major depressive disorderaspiration pneumoniahospital-acquired pneumoniahypotensionaltered conscious stateischaemic heart diseaserecurrent urosepsis
Procedures
airway insertion
Contributing factors
medication error: Nitrazepam 15mg administered instead of Mirtazapine 15mg
drug name similarity (Nitrazepam/Mirtazapine)
lack of familiarity with medications
time pressure to transfer patient to another facility
sedation-induced aspiration of gastric contents
hospital-acquired pneumonia
relative inexperience of junior nurse in medication administration
Coroner's recommendations
Commendation of Southern Health's remedial actions following internal review including annual medication administration assessments and Look-Alike Sound-Alike drug safety initiative
Implementation of electronic prescribing systems with built-in checks and balances to prevent administration of wrong drugs with similar names
Consideration of keeping non-imprest Schedule II drugs off wards unless required for current patients
Implementation of verbal confirmation protocol when two nurses check drugs from dangerous drug cupboard
Continued focus on medication safety in elderly and multi-comorbid patients given higher risk of serious consequences from sedation errors
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