Deceased
ELIZABETH MARYANNE HOLLEY
Demographics
52y, female
Date of death
2006-11-01
Finding date
2012-01-23
Cause of death
Hypoxic brain injury due to hypotension in a woman with documented electrocardiogram abnormality due to coronary artery disease and treatment with antipsychotic medications
AI-generated summary
Elizabeth Holley, 52 years old, was admitted involuntarily to a psychiatric ward with a history of three weeks of declining mental health and medication non-compliance. She received high-dose antipsychotic medications including 10g of olanzapine intramuscularly on admission. She developed a prolonged QT interval on electrocardiogram, a known complication of antipsychotic use. After experiencing dizziness and collapse, she suffered cardiac arrest requiring cardiopulmonary resuscitation. She developed refractory seizures and hypoxic brain injury, dying four days later. Post-mortem examination revealed coronary artery disease, mitral valve prolapse, and multiple pulmonary emboli. The coroner found that electrocardiogram abnormalities from antipsychotics can precipitate cardiac arrhythmias leading to cardiac arrest and brain injury, but concluded her care was within normal reasonable health care practice.
AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.
Drugs involved
Clinical conditions
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