mixed prescription drug toxicity (oxycodone and oxazepam); central nervous system depression and respiratory arrest
AI-generated summary
Sandra Germaine Hill, 67, died from mixed prescription drug toxicity (oxycodone and oxazepam) combined with alcohol on 26-27 April 2019. She had multiple chronic conditions including Waldenstrom's macroglobulinaemia, osteoarthritis, osteoporosis, depression and insomnia. She had discontinued antidepressants two months before death. Following an argument with her partner, she self-administered a fatal overdose of oxycodone and oxazepam tablets with documented suicidal intent (notes left, 'DNR' written on chest, farewell text message). Her prescriber appropriately assessed her for drug-seeking behaviour on each occasion oxycodone was prescribed and found no concerns. The coroner found no clinical failings or issues requiring recommendations.
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Specialties
general practiceoncologypathologypsychology
Drugs involved
oxycodoneoxazepamalcohol
Clinical conditions
depressioninsomniaWaldenstrom's macroglobulinaemiaosteoarthritisosteoporosisneuropathic painanxietyopioid toxicitybenzodiazepine toxicitycentral nervous system depressionrespiratory arrest
Contributing factors
self-administered overdose of oxycodone and oxazepam
depression
cessation of antidepressant medication two months prior to death
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