Rebecca Jayne Eirth, 32, died from combined alprazolam and methadone toxicity following injection of illicit drugs at her supported housing residence. She had a longstanding history of substance use disorder, commencing in adolescence, with previous attempts at rehabilitation including methadone maintenance therapy from 2010. In the months before death, staff observed escalating drug use including fentanyl, alprazolam, and methamphetamine. The coroner found no issues with methadone prescribing or dispensing by health professionals, and noted Ms Eirth sourced drugs illegally. The coroner determined her death was unintentional and could not have been reasonably prevented. Clinical lessons emphasise the challenges of managing severe, longstanding opioid use disorder and the limited ability to prevent overdose death when patients supplement prescribed methadone with illicit polysubstance use.
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