undetermined; possible mixed drug intoxication and/or adrenal insufficiency
AI-generated summary
Jennifer May Tilley, aged 58, died on 8 January 2018 with an undetermined cause, though mixed drug intoxication and adrenal insufficiency were potential contributors. She had complex medical conditions requiring chronic pethidine (opioid) therapy for gut pain management. Toxicology revealed toxic pethidine levels and additional CNS depressants (citalopram, nitrazepam) not prescribed to her, which when combined with other medications increased overdose and serotonin toxicity risk. The coroner found the prescribing regime itself appropriate given her limited medication options, but identified multiple breaches of the Poisons Act 1971 by her GP in maintaining required Schedule 8 authorities. The coroner recommended prescribers ensure current authorities, register with the DORA system, and actively monitor Schedule 8 dispensing data to prevent similar preventable regulatory failures.
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Specialties
general practicerheumatologypain medicineforensic medicinepharmacy
patient self-administration of pethidine with history of inappropriate use and medication misuse
multiple breaches of Poisons Act 1971 in Schedule 8 prescribing authorities
Coroner's recommendations
Prescribers of Schedule 8 substances should ensure they are in possession of current authorities from the Pharmaceutical Services Branch in respect of their patients
Prescribers should be registered to DORA (Drugs and Poisons Information System Online Remote Access) and have working knowledge of its use
Prescribers should access DORA when needed to enhance safe prescribing practices and monitor Schedule 8 dispensing data
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