Coronial
SAhospital

Coroner's Finding: NICHOLSON James

Deceased

James Nicholson

Demographics

65y, male

Date of death

2015-08-21

Finding date

2019-03-25

Cause of death

hypoxic ischaemic encephalopathy complicating hanging

AI-generated summary

James Nicholson, aged 65, died from hypoxic ischaemic encephalopathy following a suicide attempt by hanging while an inpatient at Noarlunga Hospital on 18 August 2015. He had undergone extensive facial cancer surgery in January 2015, followed by chemotherapy and radiotherapy with concurrent dexamethasone from March 2015. Initial dexamethasone-induced hypomania progressed to psychosis, depression, and paranoid delusions as the dose was reduced. On 14 August, after concerning behaviour and suicidal statements at home, he was admitted to hospital where Emergency Department physician Dr H. correctly diagnosed steroid-induced psychosis and placed him on an Inpatient Treatment Order. However, psychiatrist Dr O. incorrectly revoked the order the next morning, diagnosing steroid withdrawal instead. The medical team then planned discharge without psychiatric review. Critical failures included: misdiagnosis of the underlying steroid-induced syndrome, failure to maintain the ITO, cessation of one-to-one nursing observation, non-implementation of recommended antipsychotic medication, and absence of proper psychiatric follow-up before discharge. Expert evidence confirmed the presentation was classical steroid-induced psychosis requiring continued medical management, antipsychotics, and close psychiatric monitoring.

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Specialties

oncologypsychiatryemergency medicineintensive care

Error types

diagnosticcommunicationsystem

Drugs involved

dexamethasonefentanylhydromorphonepregabalinmorphineclonazepam

Clinical conditions

steroid-induced psychosissteroid-induced depressionadenoid cystic carcinoma (facial cancer)paranoid delusionssuicidal ideationchemotherapy-related toxicityopioid withdrawal syndrome

Procedures

cancer surgery with facial reconstructionchemotherapy administrationradiotherapyPEG tube insertion

Contributing factors

  • steroid-induced psychosis and depression incorrectly diagnosed as steroid withdrawal
  • revocation of Inpatient Treatment Order by psychiatrist despite psychotic presentation
  • cessation of one-to-one nursing observation
  • failure to initiate antipsychotic medication
  • absence of psychiatric review prior to planned discharge
  • miscommunication between medical and psychiatric teams regarding assessment plan
  • mismanagement of dexamethasone dosing (failure to implement recommended increase)
  • abrupt cessation of opioid analgesia contributing to mood disturbance
  • psychosocial stressor (theft of handbag triggering acute anxiety and paranoia)

Coroner's recommendations

  1. The Minister for Health should publish a reminder to the medical profession of the need to be aware of the risk of steroid-induced psychosis in patients receiving corticosteroid medication
  2. Medical professionals should be reminded that the possibility of symptoms being attributable to steroid withdrawal is much more remote than attributing symptoms to the introduction of the corticosteroid
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