Coronial
SAhospital

Coroner's Finding: NGUYEN An Hoang Le

Deceased

An Hoang Le Nguyen

Demographics

4y, male

Date of death

2015-07-14

Finding date

2019-06-12

Cause of death

acute lymphoblastic leukaemia

AI-generated summary

An Hoang Le Nguyen, a 4-year-old boy, died from acute lymphoblastic leukaemia with CNS involvement. He presented with a 4-day history of abdominal pain, lethargy, fever, and respiratory symptoms at Royal Darwin Hospital where leukaemia was diagnosed. He developed life-threatening complications including disseminated intravascular coagulation, respiratory failure requiring intubation, cerebral ischaemia, and intraocular haemorrhage. Despite appropriate management including chemotherapy, leukapheresis, neurosurgical intervention for cerebral bleeding, and stem cell transplant in Sydney, he relapsed in July 2015. Medical care was optimal and appropriately managed. The coroner found no clinical issues contributing to death and made no recommendations. This case highlights the aggressive nature of early-presenting T-cell ALL with CNS disease in young children and the limitations of current curative therapies in high-risk cases.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes.

Contributing factors

  • aggressive T-cell acute lymphoblastic leukaemia with CNS involvement
  • disease relapse despite multimodal therapy
  • high-risk leukaemia carrying inherent poor prognosis
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