A 48-year-old man with schizoaffective disorder, poorly controlled diabetes, sleep apnoea, obesity and cardiomegaly died unexpectedly at a rural hospital following acute psychotic agitation. He had absconded from a mental health facility and was apprehended by police. At the hospital, he received multiple doses of benzodiazepines and antipsychotics for sedation/behavioural management. He experienced respiratory depression from midazolam which was reversed with flumazenil. Later, after haloperidol and promethazine administration, he collapsed with apparent muscle spasm around face/neck and respiratory arrest despite resuscitation. Autopsy revealed no specific cause of death. Key clinical lessons: rural hospitals managing acutely psychotic patients face significant complexity; early transfer via specialist retrieval (not RFDS/ambulance) may be preferable; careful medication choice considering respiratory sensitivity is essential; coordination between services (local hospital, psychiatric triage, retrieval services) requires defined leadership and protocols.
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nasopharyngeal airway insertionbag and mask ventilationendotracheal intubation
Contributing factors
acute psychotic agitation
cardiomegaly with right ventricular hypertrophy
sleep apnoea with intermittent airway obstruction
obesity
morbid obesity (BMI 41)
poorly controlled chronic medical conditions
multiple sedative medications
possible dystonic reaction or laryngeal spasm
exhaustion from prolonged agitation
delay in transfer to appropriate treatment centre
fragmented transfer and retrieval services
Coroner's recommendations
Ongoing awareness by Rural and Remote Consultants of the need to assess carefully risk/safety factors and the limitations of rural hospitals in managing acutely psychotic and violent patients in rural SA
Reinforcement to transport and retrieval services to carefully risk manage and risk assess acutely psychotic patients in rural hospitals with a view to early transport where possible
Implementation of a state-wide integrated management service to provide a structured team involving local hospital staff, doctors and nurses, Rural and Remote Mental Health, MedSTAR and rural doctor groups
Establishment of a defined 'team leader' who accepts responsibility for final management decisions and leads the team through the process for acutely psychotic patients
Development of a reasonably defined 'flow chart' that all teams follow, linked with areas of critical assessment and management steps outlined, including drug use, restraint use, transport type and destination
That in according priority to the transportation of mentally ill patients, priority be given, wherever possible, to the transport of patients who are the subject of inpatient treatment orders under the Mental Health Act 2009 or who are the subject of other measures that have been invoked under that Act
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