hypovolaemic shock following bleeding from the site of a femoral angiogram
AI-generated summary
Olga Krivitch, 81-year-old woman, died from hypovolaemic shock caused by bleeding from her femoral angiogram puncture site. She was admitted for ischaemic leg and underwent unsuccessful thrombolytic therapy. Subsequently commenced on Heparin anticoagulation but therapeutic range took 38 hours to achieve, exposing her to over-anticoagulation. Critical failures included: haemoglobin levels not monitored on 25-26 January despite evidence of bleeding, resulting in massive undetected haemorrhage; over 4-hour delay between identifying haemoglobin of 54 and transfusion; and lack of experienced senior staff supervision. The Vascular Surgery Unit had no registrars on duty, only junior residents. With timely monitoring, blood transfusion and surgical intervention on 25-26 January, she likely would have survived. Key lessons: mandatory daily haemoglobin monitoring when anticoagulated; explicit instructions to junior staff; adequate senior supervision; Heparin protocols requiring haematology consultation when therapeutic range not established timely.
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femoral angiographythrombolytic therapyheparin infusionCT scansurgical repair of femoral arteryblood transfusion
Contributing factors
over-anticoagulation with heparin
delayed establishment of therapeutic anticoagulation range (38 hours)
failure to monitor haemoglobin levels on 25 and 26 January 2006 despite evidence of bleeding
lack of experienced registrar supervision
inadequate staffing in vascular surgery unit
delayed identification of haemoglobin level of 54
delayed blood transfusion (over 4 hours after critical result identified)
delayed surgical repair of bleeding site
persistent coagulopathy
lack of explicit instructions to junior staff regarding monitoring requirements
Coroner's recommendations
Minister for Health draw findings to attention of all public hospital CEOs regarding need to amend Heparin Protocols based on expert observations, including need to consult haematology if APTT therapeutic range not established timely and need to include protocol copy in patient infusion chart
Minister for Health draw to attention of hospital CEOs the desirability of identifying patient blood grouping in advance of anticoagulation therapy to facilitate timely blood transfusion
Minister for Health draw findings regarding necessity to monitor haemoglobin levels in anticoagulated patients to attention of medical schools in South Australia
Minister for Health take necessary steps to ensure wards in all public hospitals are at all times appropriately staffed
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