Global cerebral oedema due to hypoxic cerebral ischaemia following cardiac arrest, which was related to hyponatraemic seizure and cerebral salt wasting syndrome post-craniotomy, in the context of previously diagnosed glioblastoma multiforme grade IV (surgically treated)
AI-generated summary
59-year-old woman admitted with newly diagnosed grade 4 glioblastoma underwent surgery 16 days later after delays during consultant's planned leave. Post-operative complications included ischaemic stroke confirmed on imaging. Despite this, she was discharged from ICU after only 22 hours with inadequate communication of the CT findings and uncertain observation frequency on the ward. No formal neurological baseline assessment was documented pre-operatively, making post-operative neurological deterioration difficult to characterise. She was found in cardiac arrest 14 hours after ward admission, likely due to a seizure triggered by hyponatraemia. Key failures included: surgeon not handing over to colleague during week-long leave; absence of speech pathology assessment despite documented speech difficulties; failure to communicate critical CT findings to ward staff; inconsistent observation frequencies; and lack of consultant involvement in discharge planning from ICU.
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Delay of 16 days in scheduling surgery due to consultant taking planned leave without appropriate handover
Absence of formal preoperative neurological assessment and speech pathology baseline despite documented speech difficulties
Post-operative ischaemic stroke (posterior cerebral artery territory infarction) not adequately communicated to ward staff
Failure to ensure CT scan findings were handed over to receiving ward team
Inappropriate discharge from ICU to ward within 22 hours of major neurosurgery complicated by stroke
Absence of clear documentation and direction regarding frequency of neurological observations on ward
Inconsistent observation frequency (two hourly vs four hourly) with only four observations recorded over 14-hour period
Glasgow Coma Scale used as sole assessment tool despite significant expressive dysphasia making verbal component unreliable
Consultant surgeon (Dr T.) not informed of critical CT findings or clinical deterioration
Excessive intraoperative fluid administration (3 litres) contributing to dilution and subsequent hyponatraemia
Hyponatraemia (sodium 120 mmol/L) developed with no early detection or intervention
Poor communication and documentation of medical decision-making throughout admission
Family concerns raised on ward not appropriately escalated
Coroner's recommendations
Conduct in-service training on importance of documentation and reinforce policy requirements for all medical staff on neurosurgical ward, including consultants
Regular follow-up audit of medical entries to ensure documentation policy compliance
Amend clinical/case pathway for craniotomy patients with brain tumour to require comprehensive speech pathologist or neurology team review when preoperative communication deficits present, ensuring timely baseline assessment
Amend clinical/case pathway to require operating surgeon(s) to complete preoperative comprehensive detailed high cognitive function neurological assessment, clearly documented on record
Amend clinical/case pathway to consider preoperative CT/MRI scan within 3-5 days prior to surgery, with surgeon required to document reason if decision made not to arrange such imaging
Present Mrs Parsons case to junior medical and nursing neurological training to highlight importance of identifying changes in speech, restlessness and changes in patient's ability to follow commands
Conduct audit to check whether consultant to consultant discharge of neurological patients is occurring in intensive care unit in accordance with root cause analysis recommendations
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