Ruby Chen, 3 years old, died from massive air embolism during aeromedical transfer from Blackwater to Rockhampton Hospital. The fatal sequence occurred when a paramedic re-spiked a partially-used IV saline bag (containing ~115 mL) with a new giving set, allowing air to enter the bag. The bag was placed in an opaque pressure cuff that forced both fluid and air through the IV line into the patient's circulation. At 250 mL/hour infusion rate, fluid exhausted after ~24 minutes, sending ~70-100 mL of air directly into her bloodstream. Clinical lesson: never re-spike IV bags; ensure single-use spike labeling; prohibit opaque pressure cuffs in aeromedical settings; use infusion pumps when feasible. The constellation of factors—re-spiking, priming with new set, opaque pressure bag, helicopter environment—was unusual and not previously encountered in practice, but entirely preventable.
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Specialties
retrieval medicineemergency medicinepaediatricsintensive care
Error types
proceduralsystem
Clinical conditions
air embolismfebrile illnessinfluenza Adehydration
Procedures
intravenous fluid administrationre-spiking of IV bagpriming of giving setaeromedical retrieval
Contributing factors
re-spiking of partially-used IV saline fluid bag
air entering IV bag during re-spiking procedure
use of opaque pressure cuff forcing air into circulation
priming of new giving set introducing air into bag
limited fluid volume remaining in reused bag (~115 mL)
helicopter environment with low light and confined space
infusion rate of 250 mL/hour exhausting remaining fluid
use of pressure cuff instead of infusion pump
Coroner's recommendations
IV saline bags should be marked in contrasting coloured lettering (e.g., yellow on black or red on clear) with 'SINGLE SPIKE ONLY' terminology adjacent to the injection port
Education and promotion of the prohibition on re-spiking of intravenous fluid bags should occur, potentially termed 'Ruby's Rule' to aid adherence
Queensland Ambulance Service should implement their new clinical practice guideline regarding the priming of giving sets
Aeromedical retrieval services should investigate whether elimination of opaque pressure cuffs is feasible and practical, with preference for infusion pumps with alarm systems and safeguards; decision-making timeframe of six months
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