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Whittington, Frank Maurice

Deceased

Frank Maurice Whittington

Demographics

66y, male

Coroner

Tonkin

Date of death

2004-02-24

Finding date

2007-12-12

Cause of death

Coronary atherosclerosis

AI-generated summary

Frank Maurice Whittington, aged 66, died from coronary atherosclerosis on 24 February 2004, shortly after day surgery to replace a catheter on his intrathecal morphine pump. Dr Rossato and RN Couper administered a 0.26ml overdose of morphine during post-operative pump priming due to reliance on Medtronic's calculation worksheet, which failed to account for fluid already present in the pump's internal tubing in previously-primed devices. While the overdose was established, the coroner found it did not contribute to death in this highly morphine-tolerant patient. The underlying coronary artery disease and a massive meal consumed post-operatively triggered the fatal heart attack. Key clinical lessons: manufacturers must provide clear, context-specific guidance for device programming; clinicians should verify calculations independently; and pre-existing cardiac disease may remain asymptomatic despite severe pathology, particularly in pain patients receiving excellent analgesia from intrathecal delivery.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.

Specialties

anaesthesianeurosurgerypain medicinecardiologypathology

Error types

medicationsystem

Drugs involved

morphine sulphatepromethazinesertraline

Clinical conditions

coronary atherosclerosischronic coronary artery diseasecardiac failuremorphine tolerancemyocardial infarctionintrathecal opioid delivery complication

Procedures

intrathecal catheter replacementpump refilling and reprogramminglumbar punctureabdominal wound reopening

Contributing factors

  • Calculation error in post-operative morphine pump bolus dose
  • Medtronic calculation worksheet did not account for pre-filled internal tubing volume in previously-primed pumps
  • Chronic coronary artery disease with significant atheroma
  • Large meal consumption post-operatively
  • Inadequate pre-operative cardiac assessment despite 1998 chest pain history

Coroner's recommendations

  1. Section 5 of the Medtronic Manual 'Pump Implant: Critical Tasks and Procedures' should be amended to include a warning that the Postoperative Bolus Dose calculation procedure must be modified for previously-primed pumps to account for the 0.26ml internal tubing volume
  2. A second Postoperative Priming Bolus Calculation Worksheet should be developed for previously-primed pumps and added to the References and Resources section of Section 5 of the Manual
Full text

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