Coronial
NSWother

Inquest into the death of Roland Ashbolt

Deceased

Roland Ashbolt

Demographics

39y, male

Coroner

Decision ofDeputy State Coroner Lee

Date of death

2022-06-28

Finding date

2025-06-12

Cause of death

clozapine toxicity

AI-generated summary

Roland Ashbolt, a 39-year-old man remanded in custody with schizophrenia, died from clozapine toxicity. He had been prescribed clozapine (400mg daily) from January 2022 with good clinical response and therapeutic levels. On 28 June 2022, he was found unresponsive in his cell at Long Bay Correctional Centre Mental Health Unit. Post-mortem analysis showed clozapine at 4.6 mg/L (therapeutic range 0.35-0.6 mg/L), indicating one or more overdoses. Expert evidence established the clozapine level was not artifactual despite eight-day post-mortem interval. The prescription of clozapine was clinically appropriate given treatment-resistant schizophrenia and previous positive response. Administration protocols including supervised medication and oral cavity checks were appropriate. Regular cell searches and nursing checks were conducted. No evidence suggested additional preventive measures were strongly indicated. Death was classified as misadventure due to unintentional overdose.

AI-generated summary and tagging — may contain inaccuracies; refer to original finding for legal purposes. Report an inaccuracy.

Specialties

psychiatryforensic medicinegeneral medicinetoxicology

Drugs involved

clozapinevenlafaxinemirtazapine

Clinical conditions

schizophreniaclozapine toxicitytreatment-resistant schizophreniadepressive symptomsmyocarditis

Contributing factors

  • possible medication stockpiling or hoarding of clozapine
  • history of previous overdose attempts
  • history of suicidal ideation and self-harm
  • ingestion of one or more overdoses of clozapine
Full text

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